A Case of Persistent Tardive Dyskinesia in Bipolar Mania
نویسنده
چکیده
Bay CK 49 yaşında iki uçlu bozukluk tip 1 tanısı ile takipli, depresif dönemi olmayan Çin’li erkek hasta. Takibinde tam düzelme hiçbir zaman gelişmeyen hastanın hastalığına karşı içgörü azlığından dolayı 3 kere yatırılarak tedavi edildi. Hastanın beklenmeyen tardiv diskinezisi hipomanik dönemde hastalığının 15. yılından sonrasında ilk defa ortaya çıktı. Bu haraketler son manik döneminde arttı ve devamlılık gösterdi ve ayrıca manik dönemin gerilemesi ile belirtiler kayboldu. Manik dönemdeki tardiv diskinezinin görünümü ile ilgili vaka sunumları dopamin-reseptör aşırı duyarlılığı ile açıklanırken diğerlerinde hareketler sadece depresif dönemde oluşur. Bizim vakamızda tardiv diskinezi riski hastanın ilerlemiş yaşı, geçmiş dönemdeki manik hecmelerin varlığı, depresif dönemlerin olmayışı ve lityum ile ilişkili uzamış yetersiz tedavi ile artmıştır. Bay CK’nın son manik dönemin tedavisi ile işlevselliğinin en iyi seviyesine ulaştı ve sonraki tardiv diskinezi tekrarlanması önlendi.
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